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We’re excited to announce the launch of two new resources: Martindale’s ADR Checker, a quick and easy tool to support you when managing patients with adverse drug reactions, and the Palliative Care Formulary, the expert source of drug information in palliative and hospice care.

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Publication Updates

10 Mar
British National Formulary for Children logo
BNF for Children March 2020 Update

This update contains 11 significant changes and 1 new preparation.

Significant Changes: 

• Cannabidiol with clobazam for treating seizures associated with Dravet syndrome [NICE guidance].

• Cannabidiol with clobazam for treating seizures associated with Lennox–Gastaut syndrome [NICE guidance].

• Diabetic foot infections, antibacterial therapy: new guidance on management.

• Malaria, prophylaxis: updated country recommendations in the recommended regimens for prophylaxis against malaria in-line with Public Health England.

• Malaria, prophylaxis: updated guidance in-line with Public Health England recommendations.

• Mecasermin (Increlex®▼): risk of benign and malignant neoplasia [MHRA/CHM advice].

• Newborn life support image (see Life support algorithm image) updated.

• Ondansetron: small increased risk of oral clefts following use in the first 12 weeks of pregnancy [MHRA/CHM advice].

• Pneumococcal vaccine: updated guidance in-line with Public Health England recommendations.

• Sodium valproate: updated Pregnancy Prevention Programme [MHRA/CHM advice].

• Valproic acid: updated Pregnancy Prevention Programme [MHRA/CHM advice].

New Preparations: Zalkya® [ dienogest ].

For further details on changes in the BNFC click on https://www.medicinescomplete.com/#/content/bnfc/PHP107699?hspl=changes

10 Mar
Stockley's Interactions Checker_logo
Stockley’s Interaction Checker March 2020 Update

New and updated interactions now available

For March, 347 new interactions have been added, and 14 existing interactions have been updated.

10 Mar
Handbook on Injectable Drugs logo
Handbook of Injectable Drugs March 2020 Update

This update contains 1 new monograph, 115 revised monographs and 8 new MedWatch alerts.

New monographs: Lefamulin Acetate

Revised monographs: Gemcitabine Hydrochloride; Omeprazole Sodium ;Linezolid; Valproate Sodium; Azithromycin; Dexmedetomidine Hydrochloride; Fenoldopam Mesylate; Mycophenolate Mofetil Hydrochloride; Ropivacaine Hydrochloride; Amphotericin B Lipid Complex; Daptomycin; Ertapenem Sodium; Oxaliplatin; Tigecycline; Voriconazole; Ziconotide Acetate; Esomeprazole Sodium; Moxifloxacin Hydrochloride; Ceftaroline Fosamil; Telavancin Hydrochloride; Tedizolid Phosphate; Ceftolozane Sulfate-Tazobactam Sodium; Ceftazidime-Avibactam Sodium; Amikacin Sulfate; Aminophylline; Amphotericin B; Ampicillin Sodium; Ascorbic Acid; Atropine Sulfate; Butorphanol Tartrate; Calcium Chloride; Calcium Gluconate; Cefazolin Sodium; Cefoxitin Sodium; Chlorpromazine Hydrochloride; Cisplatin; Clindamycin Phosphate; Colistimethate Sodium; Cyclophosphamide; Cytarabine; Dexamethasone Sodium Phosphate; Diazepam; Diphenhydramine Hydrochloride; Dobutamine Hydrochloride; Dopamine Hydrochloride; Doxycycline Hyclate; Droperidol; Ephedrine Sulfate; Epinephrine Hydrochloride; Fat Emulsion, Intravenous; Fentanyl Citrate; Fluorouracil; Furosemide; Gentamicin Sulfate; Glycopyrrolate; Haloperidol Lactate; Heparin Sodium; Hydrocortisone Sodium Succinate; Hydromorphone Hydrochloride; Hydroxyzine Hydrochloride; Insulin; Isoproterenol Hydrochloride; Ketamine Hydrochloride; Lidocaine Hydrochloride; Magnesium Sulfate; Mannitol; Meperidine Hydrochloride; Methotrexate Sodium; Methylprednisolone Sodium Succinate; Metoclopramide Hydrochloride; Metronidazole; Morphine Sulfate; Nafcillin Sodium; Naloxone Hydrochloride; Nitroglycerin; Norepinephrine Bitartrate; Pentobarbital Sodium; Phenobarbital Sodium; Phenylephrine Hydrochloride; Phenytoin Sodium; Potassium Chloride; Potassium Phosphates; Prochlorperazine Edisylate; Propranolol Hydrochloride; Scopolamine Hydrobromide; Sodium Bicarbonate; Sodium Nitroprusside; Succinylcholine Chloride; Tobramycin Sulfate; Trimethoprim-Sulfamethoxazole; Vancomycin Hydrochloride; Verapamil Hydrochloride; Cefotaxime Sodium; Lorazepam; Nalbuphine Hydrochloride; Acyclovir Sodium; Atracurium Besylate; Bumetanide; Cefuroxime Sodium; Cyclosporine; Labetalol Hydrochloride; Pancuronium Bromide; Ceftriaxone Sodium; Handbook on Injectable Drugs-References; Aztreonam; Ceftazidime; Imipenem-Cilastatin Sodium; Ranitidine Hydrochloride; Vasopressin; Esmolol Hydrochloride; Midazolam Hydrochloride; Theophylline; Buprenorphine Hydrochloride; Carboplatin; Cefotetan Disodium; Famotidine; Ganciclovir Sodium; Ifosfamide; Mitoxantrone Hydrochloride; Enalaprilat; Vecuronium Bromide; Fluconazole; Paclitaxel; Bupivacaine Hydrochloride; Piperacillin Sodium-Tazobactam Sodium; Sufentanil Citrate; Alfentanil Hydrochloride; Granisetron Hydrochloride; Propofol; Clonidine Hydrochloride; Levofloxacin; Meropenem; Cisatracurium Besylate; Remifentanil Hydrochloride; ASHP’s Handbook on Injectable Drugs Users Guide

New MedWatch alerts on the following monographs: Alprostadil; Methylprednisolone Acetate; Levocarnitine; Cyanocobalamin; Mitomycin; Pyridoxine Hydrochloride; Sodium Chloride; Iohexol

10 Mar
AHFS Drug Information logo
AHFS March 2020 Update

This update contains 8 new monographs, 15 revised monographs, 2 discontinued monographs and 1 new MedWatch alert.

New monographs: Voxelotor; Givosiran; Enfortumab Vedotin-ejfv; Afamelanotide; Golodirsen; Ubrogepant; Imipenem, Cilastatin, and Relebactam; Fam-Trastuzumab Deruxtecan-nxki

Revised monographs: Dexmedetomidine; Mifepristone; Pregabalin; Sapropterin; Ocrelizumab; Durvalumab; Lutetium Lu 177 Dotatate; Pegvaliase-pqpz; Plazomicin; Iobenguane I 131; Phentolamine; EPINEPHrine; Loperamide; Misoprostol; Gabapentin

Discontinued monographs: daclizumab; dipivefrin

New MedWatch alerts on the following monographs: Pregabalin, Gabapentin

10 Mar
Martindale logo
Martindale: The Complete Drug Reference March 2020 Update

This update contains 10 new monographs and 7 existing monographs have been updated. Preparations have been updated for 2 countries.

New monographs:

  • Activin A-neutralising antibodies have been investigated for the treatment of muscle wasting disorders, and may be subject to abuse in sport.
  • 2-Androstenol is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • 3-Androstenol is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • 2-Androstenone is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • 3-Androstenone is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • 1,2-Dimethylpentylamine may be subject to abuse in sport.
  • 1,4-Dimethylpentylamine may be subject to abuse in sport.
  • Epiandrosterone is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • 1-Epiandrosterone is reported to be an aromatase inhibitor and may be subject to abuse in sport.
  • Methylclostebol is reported to be an anabolic androgenic steroid and may be subject to abuse in sport.

Notable revisions:

  • Deprodone is a corticosteroid used topically for various skin conditions.
  • Revaprazan is a proton pump inhibitor used for gastritis and peptic ulcer disease.
  • Guanidine hydrochloride is used in the treatment of Eaton-Lambert myasthenic syndrome.

Updated names, synonyms and codes; official standards; official preparations:

  • Drugs in Sport classification updated to reflect WADA Prohibited List 2020

Proprietary Preparations and Manufacturers updated for the following countries and regions:

  • USA†
  • UK†

† Countries updated on an ongoing basis

10 Mar
Palliative Care Formulary March 2020 Update

This update contains 5 revised monographs.

The following monographs have been fully revised: Prokinetics, Quick Clinical Guide: Bowel management in paraplegia and tetraplegia, Rectal products for constipation

The following monographs have undergone minor revision: Laxatives, Pancreatin

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