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Publication Updates

09 May
British National Formulary logo
BRITISH NATIONAL FORMULARY MAY 2023 UPDATE

This update contains 3 significant changes, 1 dose change, 3 new monographs, and 3 deleted monographs.

Significant Changes:
• Pholcodine-containing cough and cold medicines: withdrawal from UK market as a precautionary measure [MHRA/CHM advice] (see advice in Aromatic inhalations, cough preparations and systemic nasal decongestants).
• Smallpox and mpox vaccine: updated guidance for immunisation.
• Smallpox vaccine: title changed to Smallpox and mpox vaccine.

Dose Change:
• Calcipotriol with betamethasone [update to dosing].

New Monographs:
Lupkynis® [voclosporin].
Orgovyx® [relugolix].
Tecvayli® [teclistamab].

Deleted Monographs:
Botulinum toxin type B; Dipyridamole with aspirin; Pholcodine.

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

 

11 Apr
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BRITISH NATIONAL FORMULARY APRIL 2023 UPDATE

This update contains 2 significant changes, 1 dose change, 5 new monographs, and 2 deleted monographs.

Significant Changes:
• Metolazone (Xaqua®): exercise caution when switching patients between metolazone preparations [MHRA/CHM advice].
• Testosterone (Testogel®): risk of harm to children following accidental exposure [MHRA/CHM advice].

Dose Change:
• Cefotaxime [update to dosing for emergency treatment of suspected bacterial meningitis or meningococcal disease, before urgent transfer to hospital].

New Monographs:
• Lamzede® [velmanase alfa].
• Livtencity® [maribavir].
• Nexviadyme® [avalglucosidase alfa].
• Perindopril erbumine with amlodipine.
• Rezurock® [belumosudil].

Deleted Monographs:
• Bleomycin.
• Vinflunine.

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

14 Mar
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BRITISH NATIONAL FORMULARY MARCH 2023

This update contains 3 significant changes, 2 dose changes, 4 new monographs, and 1 new preparation.

Significant Changes:
• Genital system infections, antibacterial therapy: updated guidance for the management of uncomplicated genital chlamydia and non-gonococcal urethritis.
• Ibrutinib (Imbruvica®): new risk minimisation measures, including dose modification recommendations, due to the increased risk for serious cardiac events [MHRA/CHM advice].
• Osteoarthritis: updated guidance on management.

Dose Change:
• Azithromycin [update to dosing for uncomplicated genital chlamydia in children from 12 years old and adults, update to dosing for non-gonococcal urethritis in adults, and update to include dosing in children from 12 years old for uncomplicated gonorrhoea].
• Ceftriaxone [update to dosing for pelvic inflammatory disease].

New Monographs:
Lunsumio® [mosunetuzumab].
Rapibloc® [landiolol hydrochloride].
Tezspire® [tezepelumab].
Xenpozyme® [olipudase alfa].

New Preparations:
Okedi® [risperidone].

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

14 Feb
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British National Formulary February 2023 Update

This update contains 3 significant changes, 1 dose change, and 3 new monographs.

Significant Changes:
• Dupilumab (Dupixent®): risk of ocular adverse reactions and need for prompt management [MHRA/CHM advice] (advice in dupilumab and tralokinumab; see example in dupilumab).
• Ibuprofen: updated breast-feeding advice.
• Obesity: updated guidance on management.

Dose Change:
• Ibuprofen [update to dosing for acute moderate pain]

New Monographs:
Aethoxysklerol® [lauromacrogol 400]
Crysvita® [burosumab]
Mounjaro® [tirzepatide]

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

10 Jan
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British National Formulary January 2023 Update

This update contains 4 significant changes, 3 dose changes, 4 new monographs and 2 new preparations.

Significant Changes:
• Contraceptives, interactions: updated guidance.
• Depression: updated guidance on management.
• Hypertension: updated guidance for the management of patients with type 1 diabetes.
• Ozanimod (Zeposia®): new indication for ulcerative colitis.

Dose Changes:
Abilify Maintena® (aripiprazole) [addition of alternative initiation dosing].
Benlysta® (belimumab) [addition of subcutaneous dosing].
Cimzia® (certolizumab pegol) [update to dosing for ankylosing spondylitis].

New Monographs:
Drovelis® [drospirenone with estetrol].
Giapreza® [angiotensin II].
Hepcludex® [bulevirtide].
Welireg® [belzutifan].

New Preparations:
Efmody® [hydrocortisone]
Okedi® [risperidone].

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

06 Dec
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British National Formulary December 2022 Update

This update contains 1 significant change, 4 dose changes, 4 new monographs and 2 new preparations.

Significant Change:
• Herpesvirus infections: updated guidance for post-exposure prophylaxis.

Dose Changes:
• Budesonide [update to dosing for intranasal administration for rhinitis and nasal polyps].
Jorveza® (budesonide) [update to dosing for eosinophilic oesophagitis].
• Lacosamide [update to age range for monotherapy and adjunctive treatment of focal seizures with or without secondary generalisation].
• Melatonin [update to dosing for jet lag].

New Monographs:
Imcivree® [setmelanotide].
Kapruvia® [difelikefalin].
Oxbryta® [voxelotor].
Qinlock® [ripretinib].

New Preparations:
Actimorph® [morphine].
Dificlir® [fidaxomicin].

For further details on changes in the BNF click on https://www.medicinescomplete.com/#/content/bnf/PHP107699

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