AHFS Drug Information (AHFS DI) is a leading source of evidence-based drug information.

AHFS DI is a dependable, comprehensive and objective database for FDA approved drug products. Inclusion of evidence-based data on labelled and unlabelled drug use makes this a valuable reference for healthcare professionals seeking to provide their patients with safe and effective therapy.

AHFS DI is published by the American Society of Health-System Pharmacists (ASHP).

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Comprehensive: Highly detailed monographs with extensive information on the chemistry and clinical application of all FDA approved drugs

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Evidence-based: Built on evidence from primary sources and peer reviewed by over 500 pharmacists, physicians and healthcare professionals

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Dependable: Fast and easy access to content that is revalidated, revised and updated regularly as new information arrives

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Objective: The information is compiled without any influence from manufacturers, insurers, regulators or other interested parties

Publication Updates

10 Jan
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AHFS January 2023 Update

This update contains 12 new monographs, 15 revised monographs and 1 new MedWatch alert.

New monographs: Chloroprocaine (EENT); Eflapegrastim; Emtricitabine and Tenofovir Alafenamide; Emtricitabine and Tenofovir Disoproxil Fumarate; Mirvetuximab Soravtansine-gynx; Mitapivat; Sodium Phenylbutyrate and Taurursodiol; Sutimlimab; Tapinarof; Tremelimumab; Vonoprazan and Amoxicillin; Vonoprazan, Clarithromycin, and Amoxicillin.

Revised monographs: Abrocitinib (Topical); Asciminib; COVID-19 Vaccine (Moderna); COVID-19 Vaccine (Novavax); COVID-19 Vaccine (Pfizer-BioNTech); Darolutamide; Empagliflozin; Fostemsavir; Imipenem, Cilastatin Sodium, and Relebactam; Ivacaftor; Lasmiditan; Margetuximab; Naltrexone and bupropion; Peginterferon Beta-1a; Ropeginterferon Alfa-2b.

New MedWatch alert on the following monograph: Belantamab Mafodotin-blmf.

06 Dec
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AHFS December 2022 Update

This update contains 4 new monographs and 21 revised monographs.

New monographs: Omidenepag Isopropyl; Sodium Nitrite; Sodium Thiosulfate; Tebentafusp.

Revised monographs: Abiraterone; Brexanolone; Buprenorphine; Capecitabine; Ceritinib; COVID-19 Vaccine (Moderna); COVID-19 Vaccine (Pfizer-BioNTech); Dabrafenib; Dalfampridine; Enasidenib; Influenza Vaccine Live Intranasal; Influenza Vaccine Recombinant; Influenza Virus Vaccine Inactivated; Lapatinib; Lusutrombopag; Mifepristone; Misoprostol; Oxaliplatin; Tezepelumab-ekko; Vancomycin; Venetoclax.

08 Nov
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AHFS November 2022 Update

This update contains 7 new monographs and 25 revised monographs.

New monographs: DaxibotulinumtoxinA-lanm; Deucravacitinib; Dextromethorphan and Bupropion; Olipudase Alfa-rpcp; Oteseconazole; Spesolimab-sbzo (Topical); Terlipressin

Revised monographs: Abatacept; ALPRAZolam; Benzodiazepines General Statement; chlordiazePOXIDE; cloBAZam; clonazePAM; Clorazepate; COVID-19 Vaccine (Moderna); COVID-19 Vaccine (Pfizer-BioNTech); Crizotinib; diazePAM; Erlotinib; Estazolam; Flurazepam; Glecaprevir and Pibrentasvir; LORazepam; Maralixibat; Midazolam; Neratinib; Oxazepam; Panobinostat; Quazepam; Siponimod; Temazepam; Triazolam

11 Oct
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AHFS October 2022 Update

This update contains 2 new monographs and 23 revised monographs.

New monographs: COVID-19 Vaccine (Novavax); Roflumilast (Topical).

Revised monographs: Alemtuzumab (MS); Bebtelovimab; Dasiglucagon; Dimethyl Fumarate; Diroximel Fumarate; Fingolimod Hydrochloride; Gefitinib; Glatiramer Acetate; Glucagon; Glycopyrronium tosylate; Maribavir; Monomethyl Fumarate; Natalizumab; Nirmatrelvir and Ritonavir; Odevixibat; Ofatumumab (Multiple Sclerosis); Osilodrostat Phosphate; Ozanimod Hydrochloride; Ponesimod; Ruxolitinib Phosphate (Topical); Sofosbuvir and Velpatasvir; Tildrakizumab-asmn; Vismodegib.

13 Sep
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AHFS September 2022 Update

This update contains 2 new monographs and 16 revised monographs.

New monographs: Ganaxolone; Vutrisiran

Revised monographs: Alectinib; Bosutinib; Cabozantinib; Decitabine and Cedazuridine, Erdafitinib, Inotersen, Lanreotide; Lemborexant; Osimertinib; Patisiran; romiPLOStim; Ruxolitinib; Sarilumab; SORAfenib; Suvorexant; Tecovirimat.

09 Aug
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AHFS August 2022 Update

This update contains 14 revised monographs and 2 new MedWatch alerts.

Revised monographs: Abemaciclib; Anakinra; COVID-19 Vaccine (Moderna); COVID-19 Vaccine (Pfizer-BioNTech); Elbasvir and Grazoprevir; Ixekizumab; Larotrectinib; Lorlatinib; Pexidartinib; Semaglutide; Trifluridine and Tipiracil; Ustekinumab; Vandetanib; Vemurafenib

New MedWatch alerts on the following monographs: Duvelisibl; Umbralisib

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